The poxvirus ubiquitin ligase p28 manipulates the ubiquitin proteasome system

The significance of poxvirus manipulation of the host ubiquitin proteasome system has become increasingly apparent. Ubiquitin is post-translationally added to target proteins by a highly conserved enzymatic cascade, typically resulting in protein degradation via the 26S proteasome. The highly cons...

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Bibliographic Details
Main Author: Mottet, Kelly
Other Authors: Barry, Michele (Medical Microbiology and Immunology)
Format: Others
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10048/1531