The role of the Prader-Willi syndrome obesity protein, MAGEL2 in the proper functioning of circadian rhythm

MAGEL2 is one of the five genes inactivated in Prader-Willi Syndrome (PWS), a genetic disorder, manifesting with symptoms of developmental delay and morbid obesity. Magel2 is highly expressed in the suprachiasmatic nucleus, which is the location of the central clock or circadian pacemaker. Magel2 kn...

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Bibliographic Details
Main Author: Weselake, Sara Victoria
Other Authors: Wevrick, Rachel (Medical Genetics)
Format: Others
Language:en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10048/1583