Matrix metalloproteinase-2 mediates angiotensin II-induced hypertension

Angiotensin II signals cardiovascular disease through metalloproteinases including MMP-2, MMP-7 and ADAM-17/TACE. We hypothesized that these metalloproteinases regulate each other at the transcriptional level. Further, MMP-2, being a major gelatinase in cardiac and vascular tissue, could mediate ang...

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Bibliographic Details
Main Author: Odenbach, Jeffrey
Other Authors: Fernandez-Patron, Carlos (Biochemistry)
Format: Others
Language:en
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10048/1908