The roles of HSV-1 VP16 and ICP0 in modulating cellular innate antiviral responses
Infection of most cell types with herpes simplex virus (HSV) mutants lacking the activation functions of VP16 and/or ICP0 results in repression of viral gene expression. However, the human osteosarcoma cell line U2OS supports the replication of VP16 and ICP0 mutants to nearly wild type levels. Pri...
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| Format: | Others |
| Language: | en |
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2009
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| Online Access: | http://hdl.handle.net/10048/858 |