The roles of HSV-1 VP16 and ICP0 in modulating cellular innate antiviral responses
Infection of most cell types with herpes simplex virus (HSV) mutants lacking the activation functions of VP16 and/or ICP0 results in repression of viral gene expression. However, the human osteosarcoma cell line U2OS supports the replication of VP16 and ICP0 mutants to nearly wild type levels. Pri...
Main Author: | Hancock, Meaghan |
---|---|
Other Authors: | Smiley, James (Medical Microbiology and Immunology) |
Format: | Others |
Language: | en |
Published: |
2009
|
Subjects: | |
Online Access: | http://hdl.handle.net/10048/858 |
Similar Items
-
Characterization of recombinant HSV-GFP reporter viruses
by: Hou, Xiaoqing
Published: (2011) -
HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity
by: Mirna Perusina Lanfranca, et al.
Published: (2014-05-01) -
A role for cytoplasmic PML in the cellular antiviral response
by: McNally, Beth Anne
Published: (2005) -
Host Intrinsic and Innate Intracellular Immunity During Herpes Simplex Virus Type 1 (HSV-1) Infection
by: Thamir Alandijany, et al.
Published: (2019-11-01) -
The role of HSV-2 proteins ICP0 and Us3 in counteracting cellular antiviral defence
by: Wan, STEPHANIE
Published: (2014)