Tumor necrosis factor triggers the expression and activation of matrix metalloproteinases through NADPH-dependent superoxide production

Tumor necrosis factor triggers the expression and activation of matrix metalloproteinases through NADPH-dependent superoxide production

Tumor necrosis factor (TNF) is upregulated in a number of cardiomyopathies. This thesis investigates TNF in triggering the expression and activation of matrix metalloproteinases (MMPs) in pressure overload cardiac disease, and explores the role of superoxide. Cardiac pressure overload was generate...

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Bibliographic Details
Main Author: Awad, Ahmed
Other Authors: Kassiri, Zamaneh (Physiology)
Format: Others
Language:en
Published: 2010
Subjects:
tumor necrosis factor
matrix metalloproteinases
reactive oxygen species
reactive nitrogen species
pressure overload cardiac disease
neonatal cardiomyocytes and cardiofibroblasts isolation
Online Access:http://hdl.handle.net/10048/976

Internet

http://hdl.handle.net/10048/976

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