Stochastic modeling of eukaryotic transcription at the single nucleotide level

DNA is the genetic material of a cell and is copied in the form of pre-mRNA through transcription in eukaryotes. RNA polymerase II is responsible for the transcription of all genes that express proteins. Transcription is a significant source of the stochasticity in gene expression. In this thesis, I...

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Bibliographic Details
Main Author: Vashishtha, Saurabh
Other Authors: Roussel, Marc R
Language:en_US
Published: Lethbridge, Alta. : University of Lethbridge, Dept. of Chemistry and Biochemistry, c2011 2012
Subjects:
Online Access:http://hdl.handle.net/10133/3190