Model-based clustering for aCGH data using variational EM

DNA copy number alterations (CNAs) are genetic changes that can produce adverse effects in numerous human diseases, including cancer. Copy number variations (of which CNAs are a subset) are a common phenomenon and not much is known about the nature of many of the mutations. By clustering patients ac...

Full description

Bibliographic Details
Main Author: Alain, Guillaume
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/11992