Mechanisms of selective immunosuppressive effects of indoleamine 2, 3-dioxygenase and borrelidin
Indoleamine 2, 3-dioxygenase (IDO), a tryptophan degrading enzyme, is a potent immunomodulatory factor that has been considered as a promising candidate in down-regulating alloimmune responses. IDO expression generates a tryptophan-deficient environment that selectively induces apoptosis in immune c...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/36674 |