Effects of zinc on retinoic acid-induced growth inhibition in human hepatocarcinoma HepG2 cells

Retinoic acid (RA), a bioactive metabolite of vitamin A, inhibits growth in a variety of cancer cells including liver cancer. It is thought that this function of RA is achieved by modulating gene expression through complexing with retinoic acid receptors (RARs) and retinoid X receptors (RXRs), two g...

Full description

Bibliographic Details
Main Author: Ibbitson, Deanna
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/40664