Chemokine-mediated modulation of autoimmunity in type 1 diabetes

Type 1 diabetes is an autoimmune disorder characterized by destruction of insulin-producing beta cells by autoreactive T cells. Despite management of type 1 diabetes with insulin therapy, affected individuals face devastating complications, such as blindness and kidney failure. Islet transplantation...

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Bibliographic Details
Main Author: Bischoff, Loraine Helena
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/43100