A novel pathway to sequester ASC at mitochondria-associated membranes dampens inflammasome activation during early Salmonella infection
Salmonella enterica is an intracellular bacterial pathogen that injects effector proteins into host cells and induces rapid cell death. Mitochondria associated membranes (MAMs) are important contact sites between mitochondria and ER and selectively facilitate Ca²⁺ uptake from ER lumen into mitochond...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2012
|
| Online Access: | http://hdl.handle.net/2429/43102 |