Studies into the mechanistic basis for local anesthetic action on transient receptor potential cation channel subfamily V member 1 in vitro

Transient receptor potential subfamily V, member 1 (TRPV1) channels are important integrators of noxious stimuli with pronounced expression in nociceptive neurons. Local anesthetics have been shown to modulate these nonselective cation channels in vivo and in vitro. However, little is known about th...

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Bibliographic Details
Main Author: Rivera, Ricardo Enrique
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44221