High-resolution mutation detection in Caenorhabditis elegans mutants and natural isolates using array comparative genomic hybridization

An essential requirement of genetic research is the ability to identify mutations. Forward genetic screens begin by selecting for a phenotype and proceed to search for the causative mutation. Reverse genetics experiments first identify the mutation and then seek to derive the mutant phenotype, if an...

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Bibliographic Details
Main Author: Maydan, Jason Stephen
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/6683