Role of liposome mediated drug delivery and drug release in determining the therapeutic activity of liposomal formulations of mitoxantrone

Although liposomal accumulation at the target site is an important issue, the critical parameter defining the activity of a liposomal formulation is drug release, a factor that includes where, when, and how fast the therapeutic agent dissociates from the liposomal carrier. This point was investig...

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Bibliographic Details
Main Author: Lim, Howard J.
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10000