Investigating a variance-components approach for linkage analysis in quantitative traits
Model-based linkage methods have had limited success in locating quantitative trait loci (QTLs) in complex traits since the underlying genetic mechanisms are not well known. As a result, robust or model-free approaches for detecting linkage have grown in popularity. We discuss a mixed effects mode...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/12828 |