A novel mechanism for RNase E-initiated decay of 5’-protected mRNA in Escherichia coli
In Escherichia coli, 5'-terminal RNA stem-loop structures are major impediments to the rate-determining initiation of mRNA degradation catalyzed by the endonuclease RNase E. Protected RNAs do, nonetheless, decay at appreciable rates, and factors which enforce the initial barrier to decay or...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/12962 |