Metal binding properties of p97 and the trafficking of a novel iron internalization pathway by GPI-anchored p97

Iron is an essential for cellular metabolism yet excessive iron can lead to deleterious oxidative damages in the cells. Since humans have no physiological pathways for iron excretion, dietary iron absorption in the intestine is tightly regulated. Although the essential nature of iron for normal c...

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Bibliographic Details
Main Author: Tiong, Jacqueline Woang Cheing
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/13820