Ketamine disrupts synaptic transmission by interacting at AMPA/Kainate receptor channels in neocortical neurons
The dissociative anaesthetic, ketamine, is commonly known as a NMDA receptor channel blocker. However, additional mechanisms of action probably contribute to its various clinical effects. We asked if ketamine influences transmission via AMPA/kainate glutamate receptor channels. Using whole cell patc...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/13936 |