Inhibition of YB-1 alone or in combination with TMZ may improve GBM treatment

Glioblastoma is a rare, but devastating brain tumor. Recent studies showed that GBM is correlated with Y-box binding protein-1 (YB-1) overexpression both in pediatric and adult patients. YB-1 is a member of the cold shock domain protein superfamily. It performs a wide variety of cellular functions,...

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Bibliographic Details
Main Author: Gao, Yuanyuan
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/14697