Functional analysis of hepatitis C virus non-structural protein (NS) 3 protease and viral cofactor NS4A

The hepatitis C virus (HCV) was identified in 1989 as the major causative agent of transfusion-associated non-A, non-B hepatitis and today represents a worldwide health crisis with prevalence estimates of 2.2%. HCV-specific therapeutics have never been more urgently needed. One of the validated drug...

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Bibliographic Details
Main Author: Martin, Morgan Mackensie
Language:English
Published: University of British Columbia 2008
Subjects:
Online Access:http://hdl.handle.net/2429/1522