Role of SWI/SNF chromatin remodeling complex in melanoma development

Human cutaneous malignant melanoma is an aggressive form of skin cancer, for its ability to metastasize rapidly and its resistance to conventional radiotherapy and chemotherapy. The mammalian SWI/SNF complex mediates ATP-dependent chromatin remodeling processes that are critical for transcriptional...

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Bibliographic Details
Main Author: Lin, Hanyang
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/26228