The prosurvival function of interferon-gamma-inducible GTPase (IRGM3) in coxsackievirus B3 infection
Interferon-γ-inducible GTPase (IGTP, or IRGM3) is a p47 GTPase upregulated in coxsackievirus B3 (CVB3)-infected murine heart and inhibits CVB3-induced apoptosis through activation of the PI3 kinase/Akt pathway. However, the mechanism of this PI3K/Akt activation and other prosurvival functions of IG...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/26674 |