An examination of the slow inactivation and resting inactivation of Kv1.5 and ShakerIR
External H⁺ and Ni²⁺ ions inhibit Kv1.5 channels by increasing current decay during a depolarizing pulse and reducing the peak current. A similarly accelerated current decay and reduced peak current amplitude have also been described in ShakerIR channels at low extracellular pH, and in the fast inac...
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Language: | English |
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University of British Columbia
2010
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Online Access: | http://hdl.handle.net/2429/28787 |