Trace analysis of cyclophosphamide and its metabolites in urine by liquid chromatography-tandem mass spectrometry

Cyclophosphamide (CP) is an antineoplastic drug used to treat a wide variety of cancers and immune disorders. CP is also a highly toxic alkylating agent, classified as an IARC Group 1 carcinogen. Workers in health-care environments are vulnerable to occupational exposure to CP, primarily via inhalat...

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Bibliographic Details
Main Author: Troster, Charles Micah Smolkin
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/29263