Development of new tools to study drug-lipid interactions and their application to investigating amphotericin b's association with model cell membranes
The interaction of different formulations of the antifungal drug amphotericin B (AmB) with model cell membranes was studied and new techniques of measuring this interaction using electrochemical and/or spectroscopic methods were developed. Two model cell membrane systems were used: sterol-free lipid...
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| Language: | en |
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University of British Columbia
2008
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| Online Access: | http://hdl.handle.net/2429/355 |