The role of SHIP in natural killer cell licensing

Natural Killer (NK) cells comprise a unique subset of lymphocytes with innate ability to detect and kill abnormal cells. Inhibitory Ly49 receptors expressed on NK cells recognize major histocompatibility complex class I (MHC I) molecules and inhibit NK cell killing of normal cells that express high...

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Bibliographic Details
Main Author: Rytova, Valeria
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/39586