Expression of beta subunit of epithelium sodium channel and cystic fibrosis transmembrane regulator in small airways obstruction in chronic obstructive pulmonary disease
Background: Excess plugging of small airways is associated with premature death in chronic obstructive pulmonary disease (COPD). Over-expression of beta-epithelial sodium channel (β-ENaC) in airway epithelia in mice resulted in plugging of small airways while cystic fibrosis transmembrane regulator...
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| Language: | English |
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University of British Columbia
2009
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| Online Access: | http://hdl.handle.net/2429/4072 |