The role of SH2-domain inositol 5' phosphatase in the inhibition of macrophage activation
Interleukin-10 (IL-10) is an anti-inflammatory cytokine essential for maintaining immune homeostasis. One of its major targets is the macrophage where it inhibits production of pro-inflammatory cytokines, chemokines and other soluble mediators. However, the intracellular signaling mechanisms by wh...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/41998 |