Extracellular granzyme B and pathophysiological implications
Granzyme B (GzmB) is a serine protease that contributes to immune-mediated elimination of cells by initiating a tightly-regulated form of death known as apoptosis. However, during inflammation, GzmB leaks out and accumulates in the extracellular space, retains its activity, and proficiently cleav...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/42827 |