Characterization of glycosaminoglycan interaction sites and exosite inhibitors of cathepsin K
Cysteine cathepsins belong to the papain-like family and are critically involved in the pathogenesis of various diseases, such as osteoporosis and cardiovascular diseases. These disorders are associated with failures in the degradation of extracellular matrix proteins, collagens and elastins. Based...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2014
|
| Online Access: | http://hdl.handle.net/2429/45998 |