Effects of short-term supplementation of folic acid and L-5-methyltetrahydofolate on cell proliferation and the expression of folate transporters in human colorectal adenocarcinoma (Caco2) cells

Folate plays a role in the synthesis and repair of DNA and the generation of methyl groups. Folic acid (FA) is a synthetic oxidized form of folate used in food fortification and supplements in Canada. Increased colon cancer incidence has been correlated with FA fortification in several countries. Th...

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Bibliographic Details
Main Author: Hempstock, Wendy
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/46541