Islet amyloid polypeptide aggregation is a local trigger for pancreatic islet inflammation
Patients with type 2 diabetes experience an inevitable deterioration of glycemic control leading to long-term complications and dependence on exogenous insulin. Amyloid deposition, macrophage infiltration, and upregulation of pro-inflammatory cytokines are common pathological features of both type 2...
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| Language: | English |
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University of British Columbia
2014
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| Online Access: | http://hdl.handle.net/2429/46729 |