Mechanism of inhibition of adenylyl cyclase by muscarinic receptor stimulation of inhibitory g-proteins in cardiac muocytes: a biochemical approach
In the mammalian myocardium, adenylyl cyclase is under dual regulation by p adrenoceptors and muscarinic receptors via stimulatory (Gs) and inhibitory (Gj) G proteins. It is well known that activation of Gs upon stimulation of p adrenoceptors cause increase in adenylyl cyclase activity. However,...
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Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/5795 |