Mechanism-based inhibitors as in vitro and in vivo probes of glycosidase structure and mechanism
Two new classes of specific, mechanism-based glycosidase inactivators were developed: 2,2-dihalo glycosyl chlorides and 5-fluoro glycosyl fluorides. Both classes were effective against x-glucosidases, which had been hitherto resistant to similar inactivation strategies. Incubation of yeast -gluco...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/7515 |