Investigation of the effect of in vivo inhibition of dipeptidyl peptidase IV (DP IV) on glucose tolerance in Zucker rats and of DP IV expression in pancreatic beta cells
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are two hormones released from the gut post-prandially which act at the pancreatic β cell to potentiate glucose-induced insulin secretion. DP IV is the primary enzyme responsible for the cleavage and inactivati...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/8349 |