Anoxia-evoked changes in intracellular pH in acutely dissociated adult rat hippocampal neurons

The ratiometric fluorophore, 2',7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein (BCECF) was utilized to measure pHi in acutely dissociated adult rat hippocampal CA1 neurons in response to periods of anoxia of 3, 5 and 10 min duration. At 37°C, in the presence or absence of HC03-, the pH...

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Bibliographic Details
Main Author: Sheldon, Claire Alexis
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/9031