Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis

Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis

OBJECTIVE—Absence of stearoyl-CoA desaturase-1 (SCD1) in mice reduces plasma triglycerides and provides protection from obesity and insulin resistance, which would be predicted to be associated with reduced susceptibility to atherosclerosis. The aim of this study was to determine the effect of SCD1...

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Bibliographic Details
Main Authors: MacDonald, Marcia L. E., van Eck, Miranda, Hildebrand, Reeni B., Wong, Brian W. C., Bissada, Nagat, Ruddle, Piers, Kontush, Anatol, Hussein, Hala, Pouladi, Mahmoud A., Chapman, M. John, Fievet, Catherine, van Berkel, Theo J. C., Staels, Bart, McManus, Bruce M., Hayden, Michael R.
Language:English
Published: American Heart Association 2009
Subjects:
Apolipoproteins
Atherosclerosis
Hyperlipoproteinemia
Inflammation
Lipoproteins
Online Access:Arteriosclerosis, Thrombosis, and Vascular Biology, 29(3), 341-347. http://atvb.ahajournals.org/cgi/content/full/29/3/341
http://hdl.handle.net/2429/9434

Internet

Arteriosclerosis, Thrombosis, and Vascular Biology, 29(3), 341-347. http://atvb.ahajournals.org/cgi/content/full/29/3/341
http://hdl.handle.net/2429/9434

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