The metabolism of razoxane and dexrazoxane in the Sprague-Dawley rat
The objectives of this project were to use a rat model to study the stereoselective metabolism of razoxane and the metabolism of dexrazoxane to its intermediate hydrolysis products. A solid phase method for extraction of razoxane from plasma and a chiral HPLC method for the simultaneous quantitation...
| Main Author: | |
|---|---|
| Language: | en_US |
| Published: |
2007
|
| Online Access: | http://hdl.handle.net/1993/1249 |