Estrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer

INTRODUCTION Estrogen is implicated as an important factor in stimulating breast cancer cell proliferation, and presence of estrogen receptor (ER) is an indication of a good prognosis in breast cancer patients. Mcl-1 is an anti-apoptotic Bcl-2 family member that is often overexpressed in breast t...

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Bibliographic Details
Main Author: Schacter, Jennifer Leah
Other Authors: Gibson, Spencer (Biochemistry and Medical Genetics)
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1993/23211