Structural and functional studies of proteins involved in the AmpC β-lactamase induction pathway

Inducible chomosomal AmpC β-lactamase (AmpC) is present in many Gram-negative opportunistic human pathogens. Expressed in response to β-lactam antibiotics, AmpC is an enzyme that can deactivate an extended spectrum of β-lactam antibiotics and thereby promote bacterial survival. Inducible chromosom...

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Bibliographic Details
Main Author: Balcewich, Misty Dawn
Other Authors: Mark, Brian (Microbiology)
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1993/3975