The cardioprotective effects of probucol against Anthracycline and Trastuzumab mediated cardiotoxicity

Background: In breast cancer patients, the administration of Trastuzumab and Doxorubicin is associated with an increased risk of cardiotoxicity. The aim of the study was to determine if the antioxidant probucol would be useful in attenuating this drug induced cardiotoxicity. Methods: In an acute mu...

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Bibliographic Details
Main Author: Walker, Jonathan Robert
Other Authors: Jassal, Davinder S. (Physiology); Singal, Pawan K. (Physiology)
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1993/4252