Development and application of a vaccinia virus based system to study viral proteins modulating interferon expression and interferon induced antiviral activities
The interferon (IFN) system is integral to antiviral innate immunity in vertebrate hosts. Inside a cell, viral pathogen associated molecular patterns (PAMPs) trigger the IFN response, comprised of IFN induction and an IFN-induced antiviral state. However, viruses have evolved strategies to counter...
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Elsevier
2012
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Online Access: | http://hdl.handle.net/1993/5068 |