Development and application of a vaccinia virus based system to study viral proteins modulating interferon expression and interferon induced antiviral activities

The interferon (IFN) system is integral to antiviral innate immunity in vertebrate hosts. Inside a cell, viral pathogen associated molecular patterns (PAMPs) trigger the IFN response, comprised of IFN induction and an IFN-induced antiviral state. However, viruses have evolved strategies to counter...

Full description

Bibliographic Details
Main Author: Arsenio, Janilyn
Other Authors: Cao, Jingxin (Medical Microbiology)
Published: Elsevier 2012
Subjects:
E3
NS1
Online Access:http://hdl.handle.net/1993/5068