Targeting IL-12 and/or IL-23 by employing peptide-based vaccines in the amelioration of murine colitis
Overexpression of IL-12 and IL-23 has been implicated in the pathogenesis of Crohn’s disease. Targeting these cytokines with monoclonal antibodies has emerged as an effective therapy, but one with adverse reactions. In this study, we sought to develop peptide-based virus-like particle vaccines speci...
Main Author: | Guan, Qingdong |
---|---|
Other Authors: | Peng, Zhikang (Immunology) |
Published: |
Elsevier
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/1993/8113 |
Similar Items
-
Targeting IL-12 and/or IL-23 by employing peptide-based vaccines in the amelioration of murine colitis
by: Guan, Qingdong
Published: (2012) -
Increased mucosal IL-12 expression is associated with relapse of ulcerative colitis
by: Kazuhiko Uchiyama, et al.
Published: (2021-03-01) -
The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges
by: Daniele Noviello, et al.
Published: (2021-05-01) -
Targeting IL-23: Insights into the pathogenesis and the treatment of psoriasis
by: Lima Hermenio, et al.
Published: (2010-01-01) -
IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions
by: Doreen M. Floss, et al.
Published: (2020-09-01)