Zidovudine resistance-associated mutations and sequence diversity in brain-derived HIV-1 reverse transcriptase
Human immunodeficiency virus type 1 (HIV-1) infects brain cells such as glial cells, regulating in the development of neurological diseases including HIV associated dementia (HIVD). The reverse transcriptase (RT) is essential for viral replication and thus is a target of antiviral agents such as zid...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/947 |