USING THE ZEBRAFISH MODEL TO DETERMINE THE ROLE OF THE HACE1 TUMOUR SUPPRESSOR IN NORMAL DEVELOPMENT AND TUMOURIGENESIS
HACE1 is a tumour suppressor gene located at human chromosome 6q21. HACE1 is downregulated in Wilms’ tumour as well as several other human cancers. Its role in normal development remains unknown. The zebrafish has established itself as a robust model for studying vertebrate development and human ca...
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| Language: | en |
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2011
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| Online Access: | http://hdl.handle.net/10222/14384 |