TOOLS FOR IDENTIFYING FUNCTIONS OF TYPE III SECRETION SYSTEM EFFECTORS FROM SHIGELLA FLEXNERI
Shigellae are pathogenic bacteria that cause the disease shigellosis. Two methods for studying secreted effectors encoded by this pathogen’s virulence plasmid are described. First, protein microarrays were used to identify substrates of an E3 ubiquitin ligase called IpaH7.8. Second, a deletion col...
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| Language: | en |
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2013
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| Online Access: | http://hdl.handle.net/10222/22282 |