Synthesis of Lewis X Analogues and Their Use as Inhibitors in Competitive Binding Studies

Four analogues of the Lewis X trisaccharide antigen (β-D-Galp(1→4)[α-L-Fucp(1→3)]-D-GlcNAcp) in which the galactosyl residue is modified at O-4 as a methyloxy, deoxychloro, deoxyfluoro or deoxy were synthesized. The preparation of the modified 4-OMe, 4-Cl, 4-F and 4-H trichloroacetimidate galactosyl...

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Bibliographic Details
Main Author: Moore, Christopher
Other Authors: Auzanneau, France-Isabelle
Language:en
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10214/4009