Developmental Plasticity of the Cellular Hypoxia Response in Zebrafish, Danio rerio
In most organisms the cellular response to hypoxia is mediated by the master regulator hypoxia-inducible factor-1 (HIF-1). Zebrafish embryos can also arrest development (suspended animation) to tolerate low oxygen. I tested the hypothesis that induction of HIF-1 and associated target genes (eg. er...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/10214/4749 |