The role of folic acid in maintaining colorectal cancer cell DNA methylation patterns, and cancer stem cell phenotype in vitro

Folic acid is a B vitamin involved in DNA CpG methylation. Mandated dietary fortification has led to a subsequent increase in blood folate concentration which has been correlated to a simultaneous spike in colorectal cancer incidence in Canada and the US. Several human colorectal cancer cell lines w...

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Bibliographic Details
Main Author: Farias, Nathan
Other Authors: Coomber, Brenda
Language:en
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10214/7734